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More data, more answers? A 1.9 million-person health study shows why scale has limits

14.09.2026 07:03

Researchers analyzed phenotypic and linked health-record data from more than 1.9 million adults in Our Future Health, comparing demographic characteristics, disease patterns, clinical associations, an...

APOE genotype helps p-tau217 predict who may develop cognitive impairment sooner

14.09.2026 06:26

A pooled analysis of 8,582 adults from seven prospective cohorts found that higher plasma p-tau217 concentrations were associated with greater cognitive impairment risk and earlier progression, with s...

A study of ayahuasca users found a mental health pattern researchers cannot yet explain

14.09.2026 05:58

In a cross-sectional study of 808 Brazilian adults planning to attend ayahuasca ceremonies, greater prior experience with the brew was associated with lower depression, anxiety, and stress scores, as ...

Cockroaches have a reputation for surviving almost anything, but this diet proved deadly

14.09.2026 05:31

A laboratory study tested how ultra-processed, unprocessed, and mixed diets affected survival in 127 lobster cockroaches, Nauphoeta cinerea. Cockroaches fed only ultra-processed foods had higher morta...

A large US study found no overall link between fluoride in pregnancy and children’s behavior

14.09.2026 05:07

A US cohort study of 5,520 children found no overall association between prenatal exposure to fluoride in public drinking water and internalizing or externalizing behavioral problems across the primar...

Subcutaneous tarlatamab exhibits low toxicity rates in phase 1b trial

12.09.2026 13:53

Subcutaneous administration of tarlatamab was well tolerated and demonstrated preliminary antitumor activity in patients with previously treated extensive-stage small cell lung cancer (ES-SCLC), accor...

Phase 2 study highlights flexible dosing options for tarlatamab in relapsed SCLC

12.09.2026 13:49

Extended-interval dosing regimens of tarlatamab demonstrated efficacy, safety and pharmacokinetic profiles generally consistent with the established every-two-week regimen in patients with previously ...

MD Anderson trial challenges local consolidative therapy paradigm in NSCLC

12.09.2026 13:46

Adding local consolidative therapy (LCT) after induction treatment with nivolumab plus ipilimumab did not improve overall survival or progression-free survival in patients with metastatic non-small ce...

Neoadjuvant atezolizumab addition quadruples pathological responses in resectable lung tumors

12.09.2026 13:38

Patients with resectable stage II–IIIB non-small cell lung cancer (NSCLC) treated with perioperative atezolizumab plus platinum-based chemotherapy experienced a median event-free survival of 62.8 mo...

Low discontinuation rates confirm manageable safety of iza-bren

12.09.2026 13:35

An investigational EGFR x HER3 antibody-drug conjugate demonstrated promising efficacy with a tolerable safety profile in patients with previously treated EGFR-mutated non-small cell lung cancer (NSCL...