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Subcutaneous tarlatamab exhibits low toxicity rates in phase 1b trial

12.09.2026 13:53

Subcutaneous administration of tarlatamab was well tolerated and demonstrated preliminary antitumor activity in patients with previously treated extensive-stage small cell lung cancer (ES-SCLC), accor...

Phase 2 study highlights flexible dosing options for tarlatamab in relapsed SCLC

12.09.2026 13:49

Extended-interval dosing regimens of tarlatamab demonstrated efficacy, safety and pharmacokinetic profiles generally consistent with the established every-two-week regimen in patients with previously ...

MD Anderson trial challenges local consolidative therapy paradigm in NSCLC

12.09.2026 13:46

Adding local consolidative therapy (LCT) after induction treatment with nivolumab plus ipilimumab did not improve overall survival or progression-free survival in patients with metastatic non-small ce...

Neoadjuvant atezolizumab addition quadruples pathological responses in resectable lung tumors

12.09.2026 13:38

Patients with resectable stage II–IIIB non-small cell lung cancer (NSCLC) treated with perioperative atezolizumab plus platinum-based chemotherapy experienced a median event-free survival of 62.8 mo...

Low discontinuation rates confirm manageable safety of iza-bren

12.09.2026 13:35

An investigational EGFR x HER3 antibody-drug conjugate demonstrated promising efficacy with a tolerable safety profile in patients with previously treated EGFR-mutated non-small cell lung cancer (NSCL...

Tumor DNA clearance reaches 39% in novel immunomodulator and ADC combination

12.09.2026 13:31

The investigational combination of pumitamig and elfetabart drozuntecan (elfe-D) demonstrated a manageable safety profile and encouraging early antitumor activity in patients with small cell lung canc...

Stricter glucose control may affect quality of life in people living with diabetes

12.09.2026 02:33

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) shows that, in people living with diabetes (type 1 o...

Distinct EFEMP1 variants cause different forms of vision loss

12.09.2026 02:26

Scientists identified a new vision condition linked to a gene already connected to a different vision-loss disease. While the previously identified disease causes loss of central vision, the new condi...

Rare cortical neurons actively promote the transition into sleep

12.09.2026 02:22

What makes the brain fall asleep? For nearly a century, scientists have looked to structures deep within the brain for the answer.

FDA clears trial of dual-targeted CAR T-cell therapy for cancer

12.09.2026 02:16

The U.S. Food and Drug Administration this week granted permission for investigators at the University of Colorado Anschutz to conduct a clinical trial testing genetically engineered immune cells in a...